Burkholderia pseudomallei meningitis following inadequate treatment of melioidotic mycotic aneurysm

Chlebicki MP, Kurup A, Sin YK
Correspondence: Dr Maciej Piotr Chlebicki, pchlebicki@hotmail.com

ABSTRACT
We report a 64-year-old man presenting with meningitis caused by Burkholderia pseudomallei predisposed by persistent aortic graft infection following inadequate treatment of a melioidotic mycotic aneurysm. The relapse of melioidosis presenting as acute meningitis is a unique event. Successful treatment of deep-seated melioidosis can only be achieved when robust antimicrobial therapy is combined with appropriate surgical debridement.

Keywords: aortic graft infection, Burkholderia pseudomallei, melioidosis, melioidotic meningitis, meningitis, mycotic aneurysm
Singapore Med J. 2008; 49(9): e219-21