Singapore Med J 2014; 55(2): 103-105; http://dx.doi.org/10.11622/smedj.2014022
First transcatheter aortic valve implantation for severe pure aortic regurgitation in Asia
Chiam PT, Ewe SH, Chua YL, Lim YT
Correspondence: Dr Paul TL Chiam, paul.chiam.t.l@nhcs.com.sg
ABSTRACT
Transcatheter aortic valve implantation (TAVI) has become the standard of care for inoperable patients with symptomatic severe aortic stenosis (AS), and an alternative to open aortic valve replacement for patients at high surgical risk. TAVI has also been performed in several groups of patients with off-label indications such as severe bicuspid AS, and as a valve-in-valve therapy for a degenerated surgical bioprosthesis. Although TAVI with CoreValve® prosthesis is technically challenging, and global experience in the procedure is limited, the procedure could be a treatment option for well-selected patients with severe pure aortic regurgitation (AR). Herein, we report Asia’s first case of TAVI for severe pure AR in a patient who was at extreme surgical risk, with good clinical outcome at six months.
Keywords: aortic valve regurgitation, aortic valve stenosis, catheter, prosthesis, transcatheter aortic valve implantation
Singapore Med J 2014; 55(2): 103-105; http://dx.doi.org/10.11622/smedj.2014022
REFERENCES
1. Cribier A, Eltchaninoff H, Bash A, et al. Percutaneous transcatheter implantation of an aortic valve prosthesis for calcific aortic stenosis: first human case description. Circulation 2002; 106:3006-8.
http://dx.doi.org/10.1161/01.CIR.0000047200.36165.B8 |
| |
2. Leon MB, Smith CR, Mack M, et al. Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery. N Engl J Med 2010; 363:1597-607.
http://dx.doi.org/10.1056/NEJMoa1008232 |
| |
3. Makkar RR, Fontana GP, Jilaihawi H, et al. Transcatheter aortic-valve replacement for inoperable severe aortic stenosis. N Engl J Med 2012; 366:1696-704.
http://dx.doi.org/10.1056/NEJMoa1202277 |
| |
4. Smith CR, Leon MB, Mack MJ, et al. Transcatheter versus surgical aorticvalve replacement in high-risk patients. N Engl J Med 2011; 364:2187-98.
http://dx.doi.org/10.1056/NEJMoa1103510 |
| |
5. Kodali SK, Williams MR, Smith CR, et al. Two-year outcomes after transcatheter or surgical aortic-valve replacement. N Engl J Med 2012; 366:1686 -95.
http://dx.doi.org/10.1056/NEJMoa1200384 |
| |
6. Chiam PT, Chao VT, Tan SY, et al. Percutaneous transcatheter heart valve implantation in a bicuspid aortic valve. JACC Cardiovasc Interv 2010; 3:559- 61.
http://dx.doi.org/10.1016/j.jcin.2009.11.024 |
| |
7. Wijesinghe N, Ye J, Rodés-Cabau J, et al. Transcatheter aortic valve implantation in patients with bicuspid aortic valve stenosis. JACC Cardiovascular Interv 2010; 3:1122-5.
http://dx.doi.org/10.1016/j.jcin.2010.08.016 |
| |
8. Dvir D, Webb J, Brecker S, et al. Transcatheter aortic valve replacement for degenerative bioprosthetic surgical valves: results from the global valve-in-valve registry. Circulation 2012; 126:2335-44.
http://dx.doi.org/10.1161/CIRCULATIONAHA.112.104505 |
| |
9. Roy DA, Schaefer U, Guetta V, et al. Transcatheter aortic valve implantation for pure severe native aortic valve regurgitation. J Am Coll Cardiol 2013; 61:1577-84.
http://dx.doi.org/10.1016/j.jacc.2013.01.018 |
| |
