Singapore Med J 2009; 50(11): e371-e373
Granulomatous meningitis
Loy ST, Tan CWT
Correspondence: Dr Clement Tan, clement_wt_ tan@nuh.com.sg
ABSTRACT
We report idiopathic hypertrophic pachymeningitis in a previously-healthy 34-yearold Filipino man, who presented with third and sixth cranial nerve palsies, headache, vomiting and left proptosis. Magnetic resonance imaging of the brain showed diffuse dural thickening and enhancement, with mild cerebrospinal fluid lymphocytosis and slight protein elevation. The patient was treated with anti-tuberculous medications and steroids, and made good recovery. We discuss the differential diagnoses and various diagnostic tests with respect to granulomatous inflammation of the meninges.
Keywords: granulomatous lesions, idiopathic hypertrophic pachymeningitis, meningeal inflammation, pachymeningitis, sarcoidosis, tuberculosis
Singapore Med J 2009; 50(11): e371-e373