Use of adjunctive treatments in improving patient outcome in Fournier's gangrene

Ooi A, Chong SJ
Correspondence: Dr Adrian Ooi, dradrianooi@gmail.com

ABSTRACT
Fournier’s gangrene is a polymicrobial necrotising soft tissue infection (NSTI) affecting the perineum and scrotum. It is rapidly progressive and destructive, and is associated with high morbidity and mortality. Management protocol includes prompt diagnosis, early institution of antibiotic therapy and adequate wound debridement, usually requiring multiple operations. The resultant defect can be left to heal by secondary intention, or surgical coverage can be undertaken. We report Fournier’s gangrene in a 60-year-old diabetic man and his successful treatment with skin grafting, which utilised a multidisciplinary approach and adjuncts, including negative-pressure wound therapy and hyperbaric oxygen therapy. We also review the literature related to these adjuncts and discuss their usefulness in the management of NSTIs.

Keywords: Fournier’s gangrene, hyperbaric oxygen therapy, negative-pressure wound therapy
Singapore Med J 2011; 52(10): e194-e197