Aetiology and management of chronic granulomatous osteomyelitis: look before you leap

Mukhopadhyay C, Dey A, Sugandhi Rao P, Pandey V, Sripathi Rao P
Correspondence: Dr P Sugandhi Rao, psraos82@yahoo.co.in

ABSTRACT
We report a rare difficult-to-manage case of chronic granulomatous osteomyelitis due to Burkholderia pseudomallei, the category two organism with atypical sensitivity pattern. The patient was a 29-year-old who presented with a history of dull aching pain in the left thigh region for one year. Local examination revealed a diffuse swelling and tenderness. Any similar presentation should therefore always be supported by microbiological opinion to prevent prolonged morbidity, especially in immunocompromised patients.

Keywords: Burkholderia pseudomallei, chronic granulomatous osteomyelitis, melioidosis, osteomyelitis
Singapore Med J 2007; 48(2): e40–e42