Clinics in Diagnostic Imaging (85)

ST Quek, S Poddar, JBK Khoo
Correspondence: Dr S T Quek, ddiqst@nccs.com.sg

ABSTRACT
Mandibular osteoradionecrosis is a rare but well-known complication that may be seen in patients with head and neck tumours following radiation therapy. A 42-year-old man presented with painful soft tissue swelling and a discharging sinus over the right mandible. Radiographs showed osteolytic destruction. Computed tomography confirmed bony destruction and fragmentation, as well as signs of soft tissue infection. The diagnosis of mandible osteoradionecrosis complicated by infection was confirmed by biopsy and surgically. The clinical and imaging features of osteoradionecrosis are highlighted.

Keywords: nasopharyngeal carcinoma, osteoradio-necrosis, mandible, radiation therapy, osteomyelitis
Singapore Med J 2003; 44(5): 269-273